Matières premières pharmaceutiques de kétoprofène CAS 22071-15-4

Ketoprofen Pharmaceutical Raw Materials CAS 22071-15-4

Ketoprofen Basic information:
Nom: Kétoprofène
CAS: 22071-15-4
MF: C16H14O3
MW: 254.28
Standard: USP
Pureté: Qualité pharmaceutique 99%
Apparence: poudre blanche
propriétés chimiques: Blanc cristallin blanc
Emballage: 25KG / Fiber drum
Uses Ketoprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (Nsiah) avec des propriétés analgésiques et antipyrétiques.
Uses Anti-inflammatory; analgésique

Pharmacodynamique

Ketoprofen is a nonsteroidal anti-inflammatory agent (Nsiah) avec des propriétés analgésiques et antipyrétiques. Ketoprofen has pharmacologic actions similar to those of other prototypical NSAIDs, which inhibit prostaglandin synthesis. Le kétoprofène est utilisé pour traiter la polyarthrite rhumatoïde, arthrose, dysménorrhée, and alleviate moderate pain.

Mécanisme d'action

The anti-inflammatory effects of ketoprofen are believed to be due to inhibition cylooxygenase-2 (COX-2), Une enzyme impliquée dans la synthèse de la prostaglandine via la voie de l'acide arachidonique. This results in decreased levels of prostaglandins that mediate pain, fièvre et inflammation. Ketoprofen is a non-specific cyclooxygenase inhibitor and inhibition of COX-1 is thought to confer some of its side effects, such as GI upset and ulceration. Ketoprofen is thought to have anti-bradykinin activity, as well as lysosomal membrane-stabilizing action. Antipyretic effects may be due to action on the hypothalamus, resulting in an increased peripheral blood flow, vasodilatation, and subsequent heat dissipation.

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