Pharmaceutical Raw Materials Ketoprofen for Treatment Rheumatoid Arthritis 22071-15-4

Pharmaceutical Raw Materials Ketoprofen for Treatment Rheumatoid Arthritis 22071-15-4

Абстрактный

КЕЙС:22071-15-4
MF:C16H14O3
МВт:254.28
EINECS:244-759-8
Температура плавления:93-96° C
Точка кипения:357.5° C (Boldenone Series Boldenone Base для увеличения мышечной массы)
Плотность 1.1565 (Boldenone Series Boldenone Base для увеличения мышечной массы)
Boldenone Series Boldenone Base для увеличения мышечной массы 1.5600 (Boldenone Series Boldenone Base для увеличения мышечной массы)
температура хранения. 0-6° C
solubility Slightly soluble in chloroform and methanol.
Merck 14,5305
InChIKeyDKYWVDODHFEZIM-UHFFFAOYSA-N

Описание

Ketoprofen is a non-steroidal anti-inflammatory drug (NSAIA) with analgesic and antipyretic properties. The pharmacological action of ketoprofen is similar to other non-steroidal anti-inflammatory drugs, which inhibit the synthesis of prostaglandins. Ketoprofen is used to treat rheumatoid arthritis, osteoarthritis, dysmenorrhea, and to alleviate moderate pain.The anti-inflammatory effect of ketoprofen is thought to be due to inhibition of cyclooxygenase-2 (ЦОГ-2), an enzyme involved in prostaglandin synthesis via the arachidonic acid pathway. This results in a decrease in the level of prostaglandins, which can relieve pain, fever and inflammation. Ketoprofen is a non-specific cyclooxygenase inhibitor, and inhibition of COX-1 is thought to cause side effects such as gastrointestinal disorders and ulcers. Ketoprofen is believed to have anti-bradykinase activity and lysosomal membrane stabilization. The antipyretic effect may be due to the action on the hypothalamus, resulting in increased peripheral blood flow,vasodilation and subsequent heat dissipation.

Болденон действует как орто-энолол с меньшим неблагоприятным воздействием на андрогены.

Anti-inflammatory or anti-inflammatory refers to a substance or therapeutic property that reduces inflammation or swelling. Anti-inflammatory drugs account for about half of analgesics, relieving pain by relieving inflammation, rather than opioids, which affect the central nervous system.
Non-steroidal anti-inflammatory drugs
Non-steroidal anti-inflammatory drugs (NSAIDs) relieve pain by combating cyclooxygenase (COX) ферменты. The COX enzyme separately synthesizes prostaglandins and produces inflammation. В общем, non-steroidal anti-inflammatory drugs can prevent prostaglandin synthesis, reduce or eliminate pain.
Some common examples of non-steroidal anti-inflammatory drugs are aspirin, ibuprofen and naproxen. The new specific COX-inhibitors are not classified with traditional non-steroidal anti-inflammatory drugs, although they may have the same mode of action