Anesthésique local Anesthésique anodin CAS 136-47-0 Tétracaïne HCl / Chlorhydrate de tétracaïne
Chlorhydrate de tétracaïne
CAS:136-47-0
MF:C15H25ClN2O2
MW:300.82
EINECS:205-248-5
Synonymes:L AND OCAIN HYDROCHLORIDE;INTERCAIN HYDROCHLORIDE;MEETHOBALM HYDROCHLORIDE;2-(DIMETHYLAMINO)ETHYL 4-(N-BUTYLAMINO)BENZOATE HYDROCHLORIDE;2-DIMETHYLAMINOETHYL ESTER OFP-BUTYLAMINOBENZOIC ACID HYDROCHLORIDE;4-(N-BUTYLAMINO)BENZOIC ACID 2-(DIMETHYLAMINO)ETHYL ESTER HYDROCHLORIDE;4-[BUTYLAMINO]BENZOIC ACID-2-[DIMETHYLAMINO]ETHYL ESTER HYDROCHLORIDE;4-BUTYLAMINOBENZOIC ACID DIMETHYLAMINOETHYL ESTER HCL
Propriétés
Point de fusion:149°C
température de stockage. Réfrigérateur
solubility alcohol: solublesoluble 40 parts of solvent
pka8.39(at 25℃)
Water Solubility Soluble in water at 50mg/ml
Merck 14,9188
InChIKeyPPWHTZKZQNXVAE-UHFFFAOYSA-N
La description
Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
spécification
| Articles de test |
spécification |
Résultats de test |
| Apparence |
Fine, blanche, crystalline, odorless powder |
confirm |
| Identification |
ABC in Pass |
confirm |
| Solubilité |
Very soluble in water, soluble in Alcohol; insoluble in Ether and Benzene |
confirm |
| USP Reference standards |
USP Tetracaine Hydrochloride RS. USP Endotoxin RS. |
confirm |
| Point de fusion |
145~150 degree |
146.0~147.5
degree |
| Chromatographic purity |
In Pass |
confirm |
| Related substance |
Not more than the reference solution 0.05% |
confirm |
| Métaux lourds |
10 ppm |
confirm |
| PH |
4.5-6.5 |
5.8 |
| Résidu à l'allumage |
≤0.10% |
0.05% |
| Perte au séchage |
≤ 0.5% |
0.19% |
| Essai |
98.0 -101.0% |
100.1% |
| Conclusion |
Confirms USP 32 |
Usage
Tetracaine hydrochloride is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum and Tetracaine hydrochloride is used for spinal anesthesia.
Produits connexes
| Article |
product name |
CASNO. |
| 1 |
chlorhydrate de procaïne |
51-05-8 |
| 2 |
Lidocaine Hydrochloride |
73-78-9 |
| 3 |
Lidocaïne |
137-58-6 |
| 4 |
Tétracaïne HCl |
136-47-0 |
| 5 |
Benzocaine Hydrochloride |
23239-88-5 |
| 6 |
Benzocaïne |
94-09-7 |
| 7 |
Aarticaine HCl |
23964-57-0 |
| 8 |
Prilocaïne |
721-50-6 |
| 9 |
Prilocaine HCl |
1786-81-8 |
| 10 |
Levobupivacaine HCl |
27262-48-2 |
| 11 |
Ropivacaïne HCl |
132112-35-7 |
| 12 |
Ropivacaine Mesylate |
854056-07-8 |
| 13 |
Dyclonine HCl |
536-43-6 |
| 14 |
Mepivacaine HCl |
1722-62-9 |
| 15 |
Chloroprocaine HCl |
3858-89-7 |
| 16 |
Etidocaine |
36637-18-0 |
| 17 |
Tétracaïne |
94-24-6 |
Directeur commercial