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  • Follistatin 344

    CATEGORY AND TAGS:
    Peptides

     

     

    Peptide

     

    MGF (2mg) HGH 176-191 (2mg)
    PEG MGF (2mg) CJC-1295 (2mg)
    DSIP (2mg) CJC-1295 DAC (2mg)
    TB500 (2mg) GHRP-2 (5mg / 10mg)
    Oxytocin (2mg) GHRP-6 (5mg / 10mg)
    Hexarelin (2mg) Selank (5mg)
    Triptorelin (2mg) Epitalon (10mg)
    Ipamorelin (2mg) PT-141 (10mg)
    Sermorelin (2mg) Melanotan I (10mg)
    Gonadorelin (2mg / 10mg) Melanotan II (10mg)
    Tesamorelin (2mg) ACE031 (1mg)
    BPC157 (2mg) Follistatin 315 (1mg)
    AOD9604 (2mg) Follistatin 344 (1mg)
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    • Specifications

    Description:
    Follistatin 344 is an activin-binding protein that aid muscle repair process and also improve

     

    motor functions. It is is made up of 323 amino acids.

     

     

    It binds directly with activin and acts as an activin antagonist. Follistatin 344 is a selective

     

    inhibitor of biosynthesis and secretion of pituitary follicle stimulating hormone (FSH). Follistatin

     

    344 is a potent myostatin inhibitor and promotes muscle growth this is due to the fact it blocks

     

    myostatin. The peptide is preferred by athletes who are unable to exercise regularly or opt out

     

    from sports activities but need massive muscle mass. Research studies demonstrated the anti-

     

    aging and tissue rejuvenation effects of Follistatin, it is also a glycoprotein encoded by the FST

     

    gene which means that it is widely distributed in all tissues. A single follistatin gene encodes to

     

    various isoforms including FST317 and FST344.

     

     

    These isoforms are made up of 317 and 344 amino acids that promote alternative splicing of

     

    mRNA. Molecular biological studies have identified potential linkage between polycystic ovarian

     

    syndrome and follistatin genes. It was first discovered as follicle stimulating hormone compound

     

    in the ovarian follicle fluid. The human Follistatin CDNA encodes for a 344 amino acid protein

     

    with 29 amino acids signaling the sequence. The domain that encodes for the EGF has kazallike

     

    motifs and a highly acidic C-terminal. The secreted Follistatin binds to TGF-family ligand as

     

    indicated and it regulates the activity of the signaling receptors. Previous studies had shown that

     

    the polypeptide is an antagonist to activin. Moreover apart from being an antagonist to activin,

     

    Follistatin inhibits activities of other TGF-beta ligand such as GDF-11, BMP-2,-4,-6 and

     

    myostatin among others. In most cases, Follistatin is expressed in the ovaries, pituitary gland,

     

    and endometrial cells in some cases.

     

     

    Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating

     

    hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a

     

    344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding

     

    domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic

     

    Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and

     

    regulates their activity by inhibiting their access to signaling receptors. It was originally

     

    discovered as activin antagonists whose activity suppresses expression and secretion of the

     

    pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist,

     

    follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin,

     

    GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the

     

    endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein

     

    containing 344 amino acids .

     

     

     

     

    Peptide

     

    MGF (2mg) HGH 176-191 (2mg)
    PEG MGF (2mg) CJC-1295 (2mg)
    DSIP (2mg) CJC-1295 DAC (2mg)
    TB500 (2mg) GHRP-2 (5mg / 10mg)
    Oxytocin (2mg) GHRP-6 (5mg / 10mg)
    Hexarelin (2mg) Selank (5mg)
    Triptorelin (2mg) Epitalon (10mg)
    Ipamorelin (2mg) PT-141 (10mg)
    Sermorelin (2mg) Melanotan I (10mg)
    Gonadorelin (2mg / 10mg) Melanotan II (10mg)
    Tesamorelin (2mg) ACE031 (1mg)
    BPC157 (2mg) Follistatin 315 (1mg)
    AOD9604 (2mg) Follistatin 344 (1mg)

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