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Ethinylestradiol / Ethinylestradiol

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Raw Steroid Powder Ethinylestradiol / Ethynyl Estradiol CAS 57-63-6 For Treatment Of Female Hypogonadism

 

 

Quick Deails

Produktname Ethinylestradiol
CAS-Nr. 57-63-6
Chemischer Name NOVESTROL; NEO-ESTRONE; ETHYNYLESTRADIOL
Molekulargewicht 296.41
Molekularformel C20H24O2
Reinheit 99%
Verwendung A synthetic steroid with high oral estrogenic potency
Standard USP28
Aussehen Testgegenstände
Paket 1kg/aluminium foil bag or as your request
Zahlung T/T,Western Union,Bitcoin,Geld Gramm,ect.
Lieferung After payment 3-7days

 

 

Abstrakt

 

Ethinyl Estradiol is absorbed in the small intestine and reaches a serum peak about 2 Stunden später. It undergoes extensive metabolism in the liver involving the cytochrome P450 3A4 isoenzyme.

Ethinyl Estradiol and its metabolites are excreted with the bile. Due to the effect of entero hepatic circulation a second peak is seen several hours later. Individually, wide variations exist in the overall absorption process, and can be further modified by drugs that affect the enterohepatic circulation or liver enzymes.

In circulation Ethinyl Estradiol is almost fully bound to plasma albumin. It is metabolized by hydroxylation of the aromatic ring and excreted in both feces and urine, in part as glucuronide and sulfate conjugate.

Ethinyl Estradiol is hormonally effective by activating the estrogen receptor and thus is an estrogen. It finds its most common use in the estrogen-progestin combination preparations of oral contraceptives. Over time, formulations have decreased the Ethinyl Estradiol dose from as high as 100 μg to as low as 10 μg in

 

 

Spezifikation
Artikel Spezifikation Ergebnisse
Aussehen White to creamy white, geruchlos, kristallines Pulver. Testgegenstände
Löslichkeit Insoluble in water; soluble in alcohol, in Chloroform, in ether, in vegetable oils, and in solutions of fixed alkali hydroxides. Entspricht
Identifizierung EIN:IR B:UV Entspricht
Spezifische optische Drehung -28°~ -29.5° -28.3°
Melting range 180~186ºC 182.5~185.3ºC
Trocknungsverlust ≤1,0 % 0.45%
Restlösemittel Acetone≤0.5% 0.08%
Assay 97.0~102,0 % (on the dried basis) 99.43%
Particle Size 90% ≤10μ Entspricht
Fazit The product complies with specification in USP34

 

 

Anwendung

As Estinyl, EE2 was formerly used for hormone replacement therapy in menopause and the treatment of femalehypogonadism, loss of menstruation, dysmenorrhea, acne, prostate cancer, and breast cancer. jedoch, in more recent times, EE2 is mainly used in COCs. In contraception, due to concerns of unopposed estrogen action and the possible increased risk of endometrial cancer that accompanies this, EE2 is formulated in combination with progestins. EE2 is little used in menopausal hormone replacement therapy.

EE2 has been used at very high dosages (1-2 mg/Tag) in the treatment of prostate cancer.

 

Raw Steroid Powder Ethinylestradiol / Ethinylestradiol 57-63-6 For Treatment Of Female Hypogonadism

 

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Estradiol enantate HEXESTROL Bentelan
Ethynyl estradiol Progesterone Betamethasone
Algestone acetophenide Medroxyprogesterone acetate Clobetasol propionate
Ethisterone Norethindrone Halobetasol propionate
19-Norethindrone acetate Mifepristone Deflazacort
Norethisterone Enanthate Methyldienedione Tazarotene
Ethynodiol diacetate Eplerenone Ecdysone
Pregnenolone acetate Levonorgestrel Desloratadine
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Chlormadinone acetate Dienogestrel Fluorometholone Acetate
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Megestrol acetate Pregnenolon-Rohpulver CAS Dexamethasone Sodium Phosphate
Melengestrol acetate Mometasone furoate Dexamethasone palmitate
Betamethasone acetate Beclomethasone dipropionate Fluocinolone acetonide
Betamethasone Dipropionate Betamethasone 17-valerate

 

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