Bupivacaïne de série anesthésique locale de matière première pour le tueur de douleur 2180-92-9

Bupivacaïne de série anesthésique locale de matière première pour le tueur de douleur 2180-92-9

Abstrait

CAS:2180-92-9
MF:C18H28N2O
MW:288.43
EINECS:218-553-3
Point de fusion:107.5-108°
pka8.09; also reported as 8.17(à 25 ℃)
Quantité minimum d'achat 10 grammes
Categories Active Pharmaceutical Ingredients
Appearance White powder
Usage local (Dans un seul domaine) anesthetic.
Synonyms MARCAINE;BUPIVACAINE;BUPIVACAINE BASE;(.+/-.)-1-Butyl-2′,6′-pipecoloxylidide;1-Butyl-2-(2,6-xylycarbamoyl)piperidine;1-Butyl-2′,6′-pipecoloxylidide;1-butyl-2′,6′-pipecoloxylidide;1-butyl-n-(2,6-diméthylphényl)-2-piperidinecarboxamid

La description:

Bupivacaine is only found in individuals that have used or taken this drug. It is a widely used local anesthetic agent. Bupivacaine blocks the generation and the conduction of nerve impulses, vraisemblablement en augmentant le seuil d'excitation électrique dans le nerf, en ralentissant la propagation de l'impulsion nerveuse, et en réduisant le taux de montée du potentiel d'action. Bupivacaine binds to the intracellular portion of sodium channels and blocks sodium influx into nerve cells, which prevents depolarization. En général, La progression de l'anesthésie est liée au diamètre, myelination and conduction velocity of affected nerve fibers. Cliniquement, L'ordre de perte de la fonction nerveuse est le suivant: (1) douleur, (2) température, (3) touche, (4) proprioception, et (5) skeletal muscle tone. The analgesic effects of Bupivicaine are thought to potentially be due to its binding to the prostaglandin E2 receptors, subtype EP1 (PGE2EP1), which inhibits the production of prostaglandins, thereby reducing fever, inflammation, and hyperalgesia.

Application:

Bupivacaine is related chemically and pharmacologically to the aminoacyl local anesthetics. It is a homologue of mepivacaine and is chemically related to lidocaine. All three of these anesthetics contain an amide linkage between the aromatic nucleus and the amino. They differ in this respect from the procaine-type local anesthetics, which have an ester linkage.
Injection de chlorhydrate de bupivacaïne, USP – Sterile isotonic solution containing sodium chloride. The pH of the solution is adjusted to between 4 et 6.5 with sodium hydroxide or hydrochloric acid.

Bupivacaine is an anesthetic (médicament engourdissant) Cela bloque les impulsions nerveuses qui envoient des signaux de douleur à votre cerveau.
Bupivacaine is used as a local (Dans un seul domaine) anesthetic.
Bupivacaine is given as an epidural injection into the spinal column to produce numbness during labor, chirurgie, or certain medical procedures.
Bupivacaine is also used as an anesthetic for dental procedures.
Bupivacaine may also be used for purposes not listed in this medication guide.

certificat d'authenticité

Grosses soldes