Hormones peptidiques injectables

Hormones peptidiques injectables

Détails de base

La description:

PEG-MGF, ou PEGylated Mechano Growth Factor est une forme nouvelle et innovante de MGF qui surpasse plusieurs fois le MGF naturel.. MGF est une variante d'épissage du gène IGF qui augmente le nombre de cellules souches dans le muscle et permet aux fibres musculaires de fusionner et de mûrir.. Il s'agit d'un processus nécessaire à la croissance du muscle adulte. Le MGF naturel est fabriqué localement et ne passe pas dans la circulation sanguine. Le MGF synthétique est à base d’eau et lorsqu’il est administré par voie intramusculaire, voyage dans la circulation sanguine. Le MGF n’est stable dans la circulation sanguine que pendant quelques minutes.

La PEGylation est l'acte de fixer un polyéthylène glycol (CHEVILLE) structure en une autre molécule plus grosse (dans ce cas, FMG). Le PEG agit comme un revêtement protecteur et la théorie ici est que cela permettra au MGF d'être transporté dans la circulation sanguine sans être décomposé..

MGF exhibits local effects in skeletal muscle and without cannot travel through the body without modification. The problem with synthetic MGF is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, MGF only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter the bloodstream. It is also short acting so stability is not an issue. By PEGylating the MGF it is almost as efficient as local produced MGF when used intramuscularly. This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule. The polyethylene glycol groups protect the peptide but don’t surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein. T

Neurological research has shown that utilizing PEGylated MGF resulted in a longer more stable acting version of the MGF peptide in serum/blood.

Usage:

Mechano Factor (FMG) exhibits local effects in skeletal muscle and without cannot travel through the body without modification. The problem with synthetic Mechano Factor (FMG) is that it is introduced intramuscularly and is water based so it goes into the blood stream. When used this way, Mechano Factor (FMG) only remains stable in the blood stream for a few minutes. Biologically produced MGF is made locally and does not enter thebloodstream.

It is also short acting so stability is not an issue. By PEGylating the Mechano Factor (FMG) it is almost as efficient as local produced Mechano Factor (FMG) when used intramuscularly. This is accomplished by surrounding part of the peptide with a structure of polyethylene glycol, which can be attached to a protein molecule. The polyethylene glycol groups protect the peptide but do not surround it completely. The active sites of the peptide are still free to do their biological function. In this case the shell is a negative charged shield against positively charged compounds that would affect the protein.