Raw Steroid Powder Ethinylestradiol / Ethynyl Estradiol CAS 57-63-6 For Treatment Of Female Hypogonadism
Quick Deails
| Nombre del producto |
etinilestradiol |
| CAS No. |
57-63-6 |
| Nombre químico |
NOVESTROL; NEO-ESTRONE; ETHYNYLESTRADIOL |
| Peso molecular |
296.41 |
| Fórmula molecular |
C20H24O2 |
| Pureza |
99% |
| Uso |
A synthetic steroid with high oral estrogenic potency |
| Estándar |
USP28 |
| Apariencia |
Polvo cristalino blanco o casi blanco |
| Paquete |
1kg/bolsa de papel de aluminio o según su petición |
| Pago |
T / T,Western Union,Bitcoin,Pago de Pequeña Cantidad,etc.. |
| Entrega |
After payment 3-7days |
Abstracto
Ethinyl Estradiol is absorbed in the small intestine and reaches a serum peak about 2 hours later. It undergoes extensive metabolism in the liver involving the cytochrome P450 3A4 isoenzyme.
Ethinyl Estradiol and its metabolites are excreted with the bile. Due to the effect of entero hepatic circulation a second peak is seen several hours later. Individually, wide variations exist in the overall absorption process, and can be further modified by drugs that affect the enterohepatic circulation or liver enzymes.
In circulation Ethinyl Estradiol is almost fully bound to plasma albumin. It is metabolized by hydroxylation of the aromatic ring and excreted in both feces and urine, in part as glucuronide and sulfate conjugate.
Ethinyl Estradiol is hormonally effective by activating the estrogen receptor and thus is an estrogen. It finds its most common use in the estrogen-progestin combination preparations of oral contraceptives. Con el tiempo, formulations have decreased the Ethinyl Estradiol dose from as high as 100 μg to as low as 10 μg in
Especificación
| Artículo |
Especificación |
Resultados |
| Apariencia |
White to creamy white, inodoro, polvo cristalino. |
polvo cristalino blanco |
| Solubilidad |
Insoluble en agua; soluble in alcohol, en cloroformo, in ether, in vegetable oils, and in solutions of fixed alkali hydroxides. |
Cumple |
| Identificación |
A:IR B:ultravioleta |
Cumple |
| Rotación óptica específica |
-28°~ -29.5° |
-28.3° |
| Rango de fusión |
180~186ºC |
182.5~185.3ºC |
| Pérdida por secado |
≤1.0% |
0.45% |
| Solventes residuales |
Acetone≤0.5% |
0.08% |
| Ensayo |
97.0~102,0% (en base seca) |
99.43% |
| Tamaño de partícula |
90% ≤10μ |
Cumple |
| Conclusión |
El producto cumple con las especificaciones en USP34 |
Solicitud
As Estinyl, EE2 was formerly used for hormone replacement therapy in menopause and the treatment of femalehypogonadism, loss of menstruation, dismenorrea, acné, cáncer de próstata, and breast cancer. Sin embargo, in more recent times, EE2 is mainly used in COCs. In contraception, due to concerns of unopposed estrogen action and the possible increased risk of endometrial cancer that accompanies this, EE2 is formulated in combination with progestins. EE2 is little used in menopausal hormone replacement therapy.
EE2 has been used at very high dosages (1-2 mg / día) in the treatment of prostate cancer.
Esteroides hormonales femeninos relacionados
| estradiol |
estrona |
Hidrocortisona |
| Estradiol valerate |
estriol |
Acetato de hidrocortisona |
| Benzoato de estradiol |
Nilestrio |
|
| Estradiol cipionato |
Dietilstilbestrol |
Acetato de prednisona |
| Estradiol enestar |
Hexestrol |
Bentelan |
| Etinil estradiol |
Progesterona |
Betametasona |
| Acetofenida algestone |
Acetato de medroxiprogesterona |
Propionato de clobetasol |
| etisterona |
Noretonrona |
Propionato de halobetasol |
| 19-Acetato de noretinrona |
Mifepristona |
Deflazacort |
| Norethisterona enantatada |
Metildienedione |
Tazaroteno |
| Diacetato etynodiol |
Eplerenona |
Ecdisona |
| Acetato de embarazo |
Levonorgestrel |
Desloratadina |
| Lyestrenol |
Allestrenol |
Prednisolona fosfato sodio |
| Acetato de clormadinona |
Dienogestrel |
Acetato de fluorometolona |
| Acetato de ciproterona |
Drospirenona |
Acetato de dexametasona |
| Acetato de megestrol |
pregnenolona |
Fosfato de sodio de dexametasona |
| ACETATO |
Furoate de Mometasone |
Palmitato de dexametasona |
| Acetato de betametasona |
Beclometasona dipropionato |
Acetonida de fluocinolona |
| Dipropionato de betametasona |
Betametasona 17-valerar |
|
Gerente de ventas