Pharmazeutische Rohstoffe Sex Enhancement Serie Dapoxetin für Muskelaufbau 119356-77-3

Pharmazeutische Rohstoffe Sex Enhancement Serie Dapoxetin für Muskelaufbau 119356-77-3

Abstrakt

FALL:119356-77-3
MF:C21H23NO
MW:341.88
EINECS:1308068-626-2
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Beschreibung:

Dapoxetine is the first compound developed specially for the treatment of premature ejaculation (PE) bei Männern 18-64 years old.Dapoxetine works by inhibiting the serotonin transporter, Erhöhung der Serotoninwirkung am postsynaptischen Spalt, und infolgedessen die Verzögerung der Ejakulation fördern. Als Mitglied des selektiven Serotonin-Wiederaufnahmehemmers (SSRI) Familie, dapoxetine was initially created as an antidepressant. jedoch, im Gegensatz zu anderen SSRIs, dapoxetine is absorbed and eliminated rapidly in the body. Aufgrund seiner schnellen Wirkung eignet es sich zur Behandlung von PE, jedoch nicht als Antidepressivum.

Dapoxetin (dapoxetine) as a new fast SSRI, a short half life, a selective 5 – HT reuptake inhibitor (SSRI), for the treatment of premature ejaculation and erectile dysfunction. Dapoxetine is a selective 5 – HT reuptake inhibitor (SSRI), such drugs widely used to treat depression and related affective disorders.

Anwendung:

Dapoxetine is a white powder substance and water-soluble. Taken 1–3 hours before sexual activity, it is rapidly absorbed in the body. Its maximum plasma concentration (Cm) is reached 1–2 hours after oral administration.

Randomized, double blind, placebo-controlled trials have confirmed the efficacy of dapoxetine for the treatment of PE.Different dosage has different impacts on different type of PE. Dapoxetin 60 mg significantly improves the mean intravaginal ejaculation latency time (IELT) compared to that of dapoxetine 30 mg in men with lifelong PE, but there is no difference in men with acquired PE. Dapoxetin, given 1–3 hours before sexual episode, prolongs IELT, increases the sense of control and sexual satisfaction in men of 18 zu 64 years of age with PE. Since PE is associated with personal distress, interrelationship difficulty, dapoxetine provides help for men with PE to overcome this condition. Because lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as fluoxetine, paroxetine, Sertralin, fluvoxamine, and citalopram have been used as off label drugs to treat PE.

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