Oxytocin ist ein Säugetierhormon, das hauptsächlich als Neuromodulator im Gehirn wirkt. Oxytocin ist vor allem für seine Rolle bei der sexuellen Fortpflanzung bekannt, insbesondere während und nach der Geburt. Es wird in großen Mengen nach Dehnung des Gebärmutterhalses und der Gebärmutter während der Wehen freigesetzt, Geburt erleichtern, und nach Stimulation der Brustwarzen, Erleichterung des Stillens. Das Wort Oxytocin wurde vom griechischen Wort abgeleitet”, bedeutet schnelle Geburt. Das Oxytocin-Peptid wird als inaktives Vorläuferprotein aus dem OXT-Gen synthetisiert.
Oxytocin ist ein Peptid aus neun Aminosäuren (ein Nonapeptid). Sein systematischer Name ist Cystein-Tyrosin-Isoleucin-Glutamin-Asparagin-Cystein-Prolin-Leucin-Glycin-Amin (cys, Tyr, mit,gln,asn,cys, Profi, Leu, gly – NH2, oder CYIQNCPLG-NH2). Die Cysteinreste bilden eine Disulfidbindung. Oxytocin hat eine Molekülmasse von 1007 Dalton. Eine internationale Einheit (IU) Oxytocin entspricht ca 2 Mikrogramm reines Peptid. Die vertrauensbildende Eigenschaft von Oxytocin könnte Menschen helfen, die unter sozialen Ängsten und Stimmungsstörungen leiden, aber mit der Möglichkeit des Missbrauchs durch Vertrauenstricks und militärische Anwendungen.
Anwendung:
It’s sometimes known as the “cuddle hormone” or the “love hormone,” because it is released when people snuggle up or bond socially. Even playing with your dog can cause an oxytocin surge. Oxytocin is a hormone that also acts as a neurotransmitter in the brain. Some popular media have incorrectly labeled it the “love hormone,” because it is associated with good feelings and emotions. But its role in the body is much more complex than that. It is not a bliss or hug hormone, but it does appear to be connected to human emotions and the regulation of childbirth and breast-feeding.
Oxytocin is used for inducing labor, controlling bleeding after child birth, and treatment of incomplete or inevitable abortion. Oxytocin may also play a role in the higher levels of depression and interpersonal stress seen in women, said Turner. According to most psychiatrists, women experience depression twice as often as men and tend to be more affected by relationship difficulties.
Oxytocin Effects
The two main actions of oxytocin in the body are contraction of the womb (Uterus) during childbirth and lactation. Oxytocin stimulates the uterine muscles to contract and also increases production of prostaglandins which increase the contractions further. Manufactured oxytocin is sometimes given to induce labour if it has not started naturally or it can be used to strengthen contractions to aid childbirth. In Ergänzung, manufactured oxytocin is often given to speed up delivery of the placenta and reduce the risk of heavy bleeding by contracting the uterus. During breastfeeding, oxytocin promotes the movement of milk into the breast, allowing it to be excreted by the nipple. Oxytocin is also present in men, playing a role in sperm movement and production of testosterone by the testes.
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