White Solid Powder Local Anaesthesia Drugs Tetracaine hydrochloride / Tetricaine
Superiority
Zhongshan Latterson Biotechnology Co., Ltd., is a comprehensive pharmaceutical enterprise, which specialized in bio-pharmaceutical technology over 7 years. The company is located in Zhongshan City, Guangdong Province , China.
Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large or medium workshops and QA and research center with advanced equipment. At present, our main products are Anabolic Steroid series, Peptide series, Local Anesthetic series. Our products reach the advanced standard of domestic market, many of which reach the international standard, certificates contain: KOSHER , ISO 9001:2008 , GMP , SGS.
Description:
1. Tetracaine HCl is synthesized from 4-butylaminobenzoic acid. The ethyl ester is formed through an acid-catalyzed esterification reaction. Base-catalyzed transesterification is achieved by boiling the ethyl ester of 4-butylaminobenzoic acid with excess 2-dimethylaminoethanol in the presence of a small amount of sodium ethoxide.
2. Tetracaine is the T in Tac, a mixture of 5 to 12 per cent tetracaine, 5‱ (per myriad), a half per mille (0.5‰), or .05 per cent (1 part in 2000) adrenaline, and 4 or 10 per cent cocaine hydrochloride used in ear, nose & throat surgery and in the emergemcy department where numbing of the surface is needed rapidly, especially when children have been injured in the eye, ear, or other sensitive locations.
3. It is on the World Health Organization’s List of Essential Medicines, a list of the most important medication needed in a basic health system.A systematic review and meta-analysis of randomised controlled trials investigated tetracaine for use in emergency departments, especially for IV cannulation in children, in view of its analgesic and cost-saving properties – however it did not find a statistically significant improvement in first attempt cannulations.
Quick details:
Product Name: Tetracaine hydrochloride
Synonyms: Tetracaine HCL
CAS: 136-47-0
MF: C15H25ClN2O2
MW: 300.82
EINECS: 205-248-5
mp: 149°C
storage temp: Refrigerator
Appearance: White Solid
Usage: Local anesthetic; Mainly used in mucosa anesthetic.The function is stronger than Procaine and Lidocaine.
COA:
| Test Items |
Specification |
Test Results |
| Appearance |
Fine, white, crystalline, odorless powder |
confirm |
| Identification |
ABC in Pass |
confirm |
| Solubility |
Very soluble in water, soluble in Alcohol;insoluble in Ether and Benzene |
confirm |
| USP Reference standards |
USP Tetracaine Hydrochloride RS.USP Endotoxin RS. |
confirm |
| Melting point |
145~150 degree |
146.0~147.5 degree |
| Chromatographic purity |
In Pass |
confirm |
| Related substance |
Not more than the reference solution 0.05% |
confirm |
| Heavy metals |
≤10ppm |
confirm |
| PH |
4.5-6.5 |
5.8 |
| Residue on ignition |
≤0.10% |
0.05% |
| Loss on Drying |
≤ 0.5% |
0.19% |
| Assay |
98.0 -101.0% |
100.1% |
| Conclusion |
Confirms USP 32 |
Applications:
Tetracaine hydrochloride is indicated for the production of spinal anesthesia for procedures requiring two to three hours. Parenteral administration of Tetracaine hydrochloride stabilizes the neuronal membrane and prevents initiation and transmission of nerve impulses thereby effecting local anesthesia.
The onset of action is rapid, and the duration is prolonged (up to two or three hours or longer of surgical anesthesia).Tetracaine hydrochloride is detoxified by plasma esterases to aminobenzoic acid and diethylaminoethanol.
Tetracaine HCL Usage:
The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine,though, has the advantage of a rapid onset of action.
In dental anesthesia, a relative insensitivity to lidocaine can occur for anatomical reasons due to unexpected positions of nerves. Some people with Ehlers-Danlos syndrome are insensitive to lidocaine.
FAQ
1.how to package?
We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.
2.how to delivery?
Varied ways are supported such as DHL, TNT, FEDEX, HKEMS, UPS, etc.
3.How long the product could be shipped?
Most of powders are in stock, free samples are available, the product could be shipped out within 24hours after receiving the payment.
4.is there any certifications?
Of course we have.we have already get the certification of ISO9001,you can trust us,we are a reliable manufacturer.
5.how about the rate of passing customs?
It’s unnecessary to worry about the customs passing.our company 100% pass to UK, Norway, Poland, Spain, USA, Canada, Brazil; 98% pass to Germany, Russia, Australia, New Zealand.
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