Lidocaine hcl CAS: 73-78-9 White Powder for Pain Reliving Local Anaesthesia

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Lidocaine hcl CAS: 73-78-9 White Powder for Pain Reliving

Описание:

Лидокаин, also known as lignocaine, is a medication used to numb tissue in a specific area (local anesthetic).It is also used to treat ventricular tachycardia and to perform nerve blocks.Lidocaine mixed with a small amount of adrenaline (epinephrine) is available to allow larger doses for numbing, to decrease bleeding, and to make the numbing effect last longer.When used as an injectable, it typically begins working within four minutes and lasts for half an hour to three hours.Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area.

Common side effects with intravenous use include sleepiness, muscle twitching, confusion, changes in vision, numbness, tingling, and vomiting.It can cause low blood pressure and an irregular heart rate.There are concerns that injecting it into a joint can cause problems with the cartilage.It appears to be generally safe for use in pregnancy.A lower dose may be required in those with liver problems.It is generally safe to use in those allergic to tetracaine or benzocaine.Lidocaine is an antiarrhythmic medication of the class Ib type.This means it works by blocking sodium channels and thus decreasing the rate of contractions of the heart.When it is used locally as a numbing agent, local neurons cannot signal the brain.

Basic information:

Chemical name: Lidocaine hcl
MF: C14H23ClN2O
МВт: 270.8
КЕЙС: 73-78-9
Появление: Эстрадиола 17-гептаноат
Чистота: over 99%
использование: local anaesthesia
Медицинское использование:

Local numbing agent:

The efficacy profile of lidocaine as a local anaesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Следовательно, лидокаин подходит для инфильтрации, блокировать, and surface anaesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for spinal and epidural anaesthesias; лидокаин, хотя, имеет преимущество быстрого начала действия. Adrenaline vasoconstricts arteries, reducing bleeding and also delaying the resorption of lidocaine, почти вдвое увеличивает продолжительность анестезии.
Lidocaine is one of the most commonly used local anaesthetics in dentistry. It can be administered in multiple ways, most often as a nerve block or infiltration, depending on the type of treatment carried out and the area of the mouth worked on.

For surface anaesthesia, several formulations can be used for endoscopies, перед интубацией, и т.д. Buffering the pH of lidocaine makes local numbing less painful.
Капли лидокаина можно закапывать в глаза при непродолжительных офтальмологических процедурах.. There is tentative evidence for topical lidocaine for neuropathic pain and skin graft donor site pain.As a local numbing agent, it is used for the treatment of premature ejaculation.

Heart arrhythmia:

Lidocaine is also the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (при остром инфаркте миокарда, отравление дигоксином, кардиоверсия, или катетеризация сердца) если амиодарон недоступен или противопоказан. По этому показанию после дефибрилляции следует назначить лидокаин., СЛР, and vasopressors have been initiated. A routine preventative dose is no longer recommended after a myocardial infarction as the overall benefit is not convincing.

Epilepsy:

А 2013 review on treatment for neonatal seizures recommended intravenous lidocaine as a second line treatment, if phenobarbital fails to stop seizures.

Other:

Inhaled lidocaine can be used as a cough suppressor acting peripherally to reduce the cough reflex. This application can be implemented as a safety and comfort measure for patients who have to be intubated, as it reduces the incidence of coughing and any tracheal damage it might cause when emerging from anaesthesia.

Лидокаин, along with ethanol, ammonia, and acetic acid, may also help in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.
For gastritis, drinking a viscous lidocaine formulation may help with the pain.

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