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  • Pirfenidone Raw powder CAS 53179-13-8 Bodybuilding

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    Minimum Order Quantity: 10g
    Price: Negotiable
    Packaging Details: Camouflage
    Delivery Time: 3-7work days
    Payment Terms: MoneyGram, Western Union, T/T,bitcoin
    Supply Ability: 100kg
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    • Specifications

    Pirfenidone Raw powder CAS 53179-13-8 Bodybuilding Fast and Safe Delivery

    Quick Detail:

    Product Name: Pirfenidone
    Synonyms: amr-69
    CAS: 53179-13-8
    MF: C12H11NO
    MW: 185.22
    mp: 96-97°C
    storage temp: Store at RT
    solubility DMSO: ≥10 mg/mL, soluble
    appearance: Off-White Solid

    Description:

    In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation. Pirfenidone can inhibit the TGF – beta – 1 inducing fibroblast collagen formation. Inhibition of PDGF, FGF and TGF – beta – 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the treatment of nude mice.

    Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.

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