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  • Local anesthetics APIs Lidocaine Base CAS 137-58-6 Pharmaceutical Raw Material

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    Model Number : CAS 137-58-6
    Certification : ISO9001
    Place of Origin : China
    MOQ : 10g
    Price : Negotiation
    Payment Terms : L/C, T/T, Western Union, MoneyGram,Paypal
    Supply Ability : Enough in stock
    Delivery Time : Within 12 hours after payment (Week day)
    Packaging Details : Discreet Packing ways for your choice
    Assay : 99%
    Formula : C14H23N2O
    Appearance : White crystalline powder
    Usage : Local anesthetics, used for infiltration anesthesia, nerve block, etc.
    Product Name : Lidocaine Base
    EINECS : 205-302-8
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    • Specifications

    Local anesthetics APIs Lidocaine Base CAS 137-58-6 Pharmaceutical Raw Material

    Quick Detail :

    Lidocaine Base
    Product Name: Lidocaine Base
    Synonyms: 2-(Diethylamino)-N-(2,6-dimethylphenyl)-acetamide; Lignocaine; 2-diethylaminoacet-2,6-xylidide; Lidocaine; Xylocaine; N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide; 2-[(2,6-dimethylphenyl)amino]-N,N-diethyl-2-oxoethanaminium
    CAS Registry Number: 137-58-6
    Assays: 99%
    Packaging: 25kg/drum
    Molecular Formula: C14H23N2O
    Molecular Weight: 235.3447
    EINECS: 205-302-8

    Appearance: White crystalline powder
    Usage: Local anesthetics, used for infiltration anesthesia, nerve block, etc.
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    Description :

    Lidocaine/prilocaine is a eutectic mixture of equal quantities (by weight) of lidocaine and prilocaine. A 5% emulsion preparation, containing 2.5% each of lidocaine/prilocaine, is marketed by Eutectic Mixture of Local Anesthetics.The lidocaine/prilocaine combination is indicated for dermal anaesthesia. Specifically it is applied to prevent pain associated with intravenous catheter insertion, blood sampling, superficial surgical procedures; and topical anaesthesia of leg ulcers for cleansing or debridement. Also, it can be used to numb the skin before tattooing as well as electrolysis and laser hair removal.The efficacy profile of lidocaine as a local anesthetic is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block, and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias; lidocaine, though, has the advantage of a rapid onset of action. Epinephrine (adrenaline) vasoconstricts arteries, reducing bleeding and also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia, several available formulations can be used e.g. for endoscopies, before intubations, etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.

    Applications :

    Lidocaine is also the most important class-1b antiarrhythmic drug; it is used intravenously for the treatment of ventricular arrhythmias (for acute myocardial infarction, digoxin poisoning, cardioversion, or cardiac catheterization) if amiodarone is not available or contraindicated. Lidocaine should be given for this indication after defibrillation, CPR, and vasopressors have been initiated. A routine prophylactic administration is no longer recommended for acute cardiac infarction; the overall benefit of this measure is not convincing.

    Inhaled lidocaine can be used as an antitussive (cough suppressor) acting peripherally to reduce the cough reflex. This application can be implemented as a safety and comfort measure for patients who have to be intubated, as it reduces the incidence of coughing and any tracheal damage it might cause when emerging from anesthesia.Lidocaine, along with ethanol, ammonia, and acetic acid, has also been proven to be effective in treating jellyfish stings, both numbing the affected area and preventing further nematocyst discharge.

    Specification :

    Product name Lidocaine Base
    Related Products Benzocaine , Lidocaine Hydrochloride
    CAS register number 137-58-6
    Standard USP28
    Molecular formula C14H23N2O
    Storage Shading, Confined Preservation
    M. W 235.3447
    Appearance White crystalline powder
    Package 1kg/aluminium foil bag or as required
    Usage can be used as pharmaceutical material
    Minimum order quantity 100g
    Shipping By express courier
    Shipping leading time Within 12 hours after payment (Week day)
    Payment options Western Union, MoneyGram, T/T
    Price Negotiated

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