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Nootropique

» Nootropique

Uniforme

CATÉGORIE ET ​​ÉTIQUETTES:
Nootropique

CAS:272786-64-8
MF:C13H15FN2O3S
MW:298.3332032
Synonymes:UnifiraM;2-[(4-Fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-un]pyrazin-6(2H)-un;(8aR)-2-[(4-fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-un]pyrazin-6(2H)-un;Pyrrolo[1,2-un]pyrazin-6(2H)-un, 2-[(4-fluorophenyl)sulfonyl]hexahydro-

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  • Caractéristiques

API Nootropic Unifiram Powder For Alzheimer Disease Treatment CAS 272786-64-8

Uniforme

CAS:272786-64-8

MF:C13H15FN2O3S

MW:298.3332032

Synonymes:UnifiraM;2-[(4-Fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-un]pyrazin-6(2H)-un;(8aR)-2-[(4-fluorophenyl)sulfonyl]hexahydropyrrolo[1,2-un]pyrazin-6(2H)-un;Pyrrolo[1,2-un]pyrazin-6(2H)-un, 2-[(4-fluorophenyl)sulfonyl]hexahydro-

La description

Uniforme (DM232) is another recent entrant in the Racetam family which is structurally similar to an ampakine and is closely related to Sunifiram (DM235), with the first studies on the drug being published in 2003. More studies need to be conducted to fully elucidate theeffects of Unifiram, but it appears to be effective as a Nootropic and as an anti-amnesic.

Unifiram is a relatively new nootropic drug that just might be one of the most powerful brain supplements ever invented.

According to an article in Drug Development Research, this compound boasts a potency approximately 1,000 times greater than currently available nootropics like Piracetam and Aniracetam.

Studies have shown that Unifiram has a highly positive effect on memory and cognitive activity similar to those exhibited by the more popular Racetams.

How does Unifiram Powder Work?

Unifiram is a positive allosteric modulator of your AMPA receptors (also known as -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors).

As an Ampakine, Unifiram effects glutamate uptake in the brain causing better synaptic transmission between neurons.

Unifiram also stimulates acetylcholine production making its mechanism of action very similar to Noopept, Pramiraceta, Oxiracetam and other racetam nootropics.

Avantages

In the studies conducted, Unifiram was noted to have three primary benefits: anti-amnesia, acetylcholine agonism, and anti-sedative and anti-hypnotic effects. Two of the studies on Unifiram and its analogs focused on its ability to reverse the amnesic effects of AMPA antagonists and its precognitive effects utilizing the Mouse Passive Avoidance test for their experimental methodology. Another study noted that Unifiram appears to increase acetylcholine release in rats; acetylcholine is very strongly correlated to memory and learning. There was one other study done that found, on top of being an anti-amnesic, Unifiram reduces the effects of barbiturates especially the effects of hypnosis and sedation

Unifiram Dosing

In the few studies done, the most common dose was .1mg/kg in both mice and rats and was found to be anti-amnesic in the water maze test ; this dose works out to roughly 2mg in an adult human (70kgs). One study also used 1mg/kg in rats and found it to have anti-amnesic effects in rats; this dose would be ~17mg for a healthy adult human (70kgs)

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