Anti – Paining Local Anesthetic Prilocaine

Anti – Paining Local Anesthetic Prilocaine Safe Pass

Nombre del producto: prilocaína
As:2- (propilamino) propa-namide; Prilocaine base (propilamino) propion-o-toluidide;
CASO: 721-50-6
EINECS: 211-957-0
Fórmula molecular: C13H20N2O
Peso molecular: 220.31
InChI: InChI = 1 / C13H20N2O / c1-4-9-14-11 (3) 13 (16) 15-12-8-6-5-7-10 (12) 2 / h5-8,11,14H, 4, 9H2, 1 to 3H3, (H, 15, 16)
Molecular structure: prilocaine 721-50-6
Water-soluble: soluble in water and ethanol, slightly soluble in chloroform
Propiedades:
nature:
Needle crystal. The temperature of 37-38 °C, the boiling point of 159-162 °C (0.133 kPa), Solución antibacteriana necesaria en alcohol bencílico de aceite esteroide (nD20) 1.5299. The hydrochloride salt ([1786-81-8]) was a white crystalline powder. Punto de fusion 167-168 °C. Soluble in water and ethanol, slightly soluble in chloroform. Pickle astringent bitter, inodoro.

Aplicaciones

Proparacaine hydrochloride and tetracaine are also indicated to produce local anesthesia prior to surgical procedures such as cataract extraction and pterygium excision, usually as an adjunct to locally injected anesthetics.
Ophthalmic solutions used for intraocular procedures should be preservative-free. Preservatives may cause damage to the corneal epithelium if a significant quantity of solutionenters the eye through the incision.

Prilocaine Descriptions:

Prilocaine cream is a local anesthetic. It works by blocking nerves from transmitting painful impulses to the brain.

As Prilocaine has low cardiac toxicity, Prilocaineis commonly used for intravenous regional anaesthesia (IVRA).

In some patients, ortho-toluidine, a metabolite of prilocaine, may cause methemoglobinemia, which may be treated with methylene blue. Prilocaine may also be contraindicated in people with sickle cell anemia, anemia, or symptomatic hypoxia.

People with pseudocholinesterase deficiency may have difficulty metabolizing this anesthetic.