Pharmaceutical Raw Materials Trilostane For Breast Cancer Treatment
Überlegenheit
Zhongshan Latterson Biotechnology Co., GmbH., ist ein umfassendes Pharmaunternehmen, die sich auf biopharmazeutische Technologie spezialisiert haben 7 Jahre. Das Unternehmen befindet sich in der Stadt Zhongshan, Provinz Guangdong , China.
Unsere Fabrik umfasst eine Fläche von 33500 Quadratmeter, mit sauberer Umgebung und schönem Layout. Es gibt mehrere große oder mittlere Werkstätten und ein QS- und Forschungszentrum mit fortschrittlicher Ausrüstung. Derzeit, Unsere Hauptprodukte sind anabole Steroide, Peptid-Serie, Lokalanästhesie-Serie. Unsere Produkte erreichen den fortgeschrittenen Standard des heimischen Marktes, viele davon erreichen den internationalen Standard, Zertifikate enthalten: KOSCHER , ISO 9001:2008 , GMP , SGS.
Schnelle Details:
Trilostane
CAS-Nr.: 13647-35-3
Reinheit: 98.5%Mindest
MF: C20H27NO3
EINECS-Nr.: 237-133-0
Aussehen: White to off-white power
Type: Antineoplastic Agents
Grade Standard: Medicine Grade
Verpackung: As customers requirments
Verwendung: Anti-tumor drugs and immunosuppressants
Beschreibung
Trilostane, that is 4α, 5α-epoxy-2-cyano-3,17β-diol, can reversibly inhibit 3β-hydroxy steroid dehydrogenase and △5, 4-isomerase in the adrenal cortex to block the biosynthesis of mineralocorticoid and glucocorticoid. In 1980, it was approved for the treatment of hyperaldosteronism and cortisol excess disease in the United Kingdom. In 1985, it was approved for the treatment of Cushing’s syndrome in the United States, which is adrenal cortex hyperactivity disorder. In view of the older animals, especially older dogs are susceptible to Cushing’s syndrome. Trilostane can relieve the disease symptoms of more than 90% of dogs, and improve their quality of life. So the drug has also been granted for the treatment of animals in the United Kingdom. Trilostane itself has no hormonal activity. Its side effects is less, and its safety and tolerability are also particularly good.
Anwendung
1) Trilostane,The anti estrogen steroids drug Trilostane was previously available in the United Kingdom for use in humans under the brand name Modrenal for the treatment of Cushing’s disease and for breast cancer. It was approved in the United States in 2008 for the treatment of Cushing’s disease (hyperadrenocorticism) in dogs under the brand name Vetoryl.
2) It was available by prescription in the UK under the Vetoryl brand name for some time before it was approved in the US. The drug is also used to treat the skin disorder Alopecia X in dogs. It is also the first drug approved to treat both pituitary- and adrenal-dependent Cushing’s in dogs. This prescription drug works by stopping the production of cortisol in the adrenal glands.
3) Trilostane,The anti estrogen steroids drug Vetoryl is used to treat Cushing’s syndrome (also known as Cushings disease or hyperadrenocorticism). This is a hormone problem associated with abnormally high levels of cortisone in the blood stream of affected dogs. The main symptoms caused are excessive thirst and hunger. It also affects the dog’s appearance and reduces its quality of life. Dogs may show hair loss, weight gain, lethargy, loss of bladder control and a bloated stomach.
4) Trilostane,Cushing’s disease is a condition that will be present in the dog’s system for the rest of its life and will need to be treated continually. Vetoryl tackles this problem in the pituitary and adrenal glands. Cortisol levels are reduced which leads to a reduction in symptoms and Vetoryl can make a difference in just three months.
5) Trilostane,The capsules are available in four strengths depending on the size of the dog and should only be prescribed by a vet. There are a number of contra-indications which should be taken into consideration prior to treatment. Dogs that are pregnant or who have problems with the liver or kidneys should not take this medication.
Indications
Trilostane can inhibit 3β-dehydrogenase in the synthesis of corticosteroids, and decrease the synthesis of cortisol and aldosterone. It also can be used in the treatment of Cushing’s syndrome (hypercortisolism) and primary aldosteronism. But the efficacy to treat Cushing’s syndrome (hypercortisolism) is not as metyrapone. This product also has a significant role in lowering blood testosterone levels, which may be related with that its synthesis is inhibited.
FAQ
1.how to package?
We have professional team for package and shipment. Special way to ship 100 grams to 100kg powders at one time to your country. Fast and discreet shipment could be arranged for customs pass Guaranteed.
2.how to delivery?
Varied ways are supported such as DHL, TNT, FEDEX, HKEMS, UPS, etc.
3.How long the product could be shipped?
Most of powders are in stock, free samples are available, the product could be shipped out within 24hours after receiving the payment.
4.is there any certifications?
Of course we have.we have already get the certification of ISO9001,you can trust us,we are a reliable manufacturer.
5.how about the rate of passing customs?
It’s unnecessary to worry about the customs passing.our company 100% pass to UK, Norway, Poland, Spain, USA, Kanada, Brasilien; 98% pass to Germany, Russland, Australien, New Zealand.
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