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Intelligente Drogen

» Intelligente Drogen

Pharmaceutical Intermediate Sunifiram Powder Top Quality

KATEGORIE UND TAGS:
Intelligente Drogen
Zertifizierung: GMP, SGS , ISO 9001:2008 , KOSCHER
Modell-Nr: 314728-85-3
Mindestbestellmenge: Verhandlung
Lieferzeit: Normalerweise innerhalb 7 Arbeitstage
Zahlungsbedingungen: Western Union, MoneyGram, Banküberweisung, Bitcoin
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Pharmaceutical Intermediate Sunifiram Powder Top Quality

 

Basisinformation.

 

Produktname: Sunifiram
Alias: DM-235
FALL: 314728-85-3
MF: C14H18N2O2
MW: 246.30492
Aussehen: Off-white to white crystalline powder

 

Abstrakt

Sunifiram is one of the newest nootropics on the market to smart drugs family. It is considered to be in the ampakine family of supplements. It increases one’s attention span, Entscheidung fällen, and learning abilities. Although it is believed to work much like Piracetam, it is highly potent in comparison. The structure is similar, but some have reported Sunifiram being 1000 times more potent. In terms of its potency, it’s comparable to Noopept.

It is being researched as a memory enhancer, potentially treating Alzheimer’s patients. It provides a wide variety of benefits including; increased attention span, improved focus, and increased learning potential. It has become very popular since its release, as the benefits are high and the side-effects are low.

 

Sunifiram Applications:

This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.

Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).

This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation.Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.

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