IGF-1 LR3 [mg/Durchstechflasche] FALL: 946870-92-4 Fördern Sie den Muskelaufbau effizient und sicher

Muskelaufbau IGF-1 LR3 [mg/Durchstechflasche] FALL: 946870-92-4 Fördern Sie den Muskelaufbau effizient und sicher

Schnelle Details:

Beschreibung:

IGF-1 LR3, auch bekannt als Long-Arginin-3-IGF-1, ist ein Analogon von menschlichem IGF-1, das modifiziert wurde, um a 13 amino acid N-terminus extension and the substitution of Arginine for Glutamic Acid at position 3. As a result of these modifications, IGF-1 LR3 is approximately three times more potent than IGF-1 and possesses an increased half-life due to lowered affinity for binding to the Insulin-Like Growth Factor-Binding Proteins (IGFBPs). IGF-1 LR3 retains the ability to bind agonistically to the IGF-1 receptor with improved metabolic stability, relative to IGF-1. The supplementation of mammalian cell cultures with Long R3 IGF-1 at a much lower concentration results in more highly elevated productivity than with standard concentrations of insulin and/or standard IGF-1. IGF-1 LR3 is more able to stimulate the type 1 IGF receptor and thus induce a higher level of activation of intracellular signaling, which is responsible for promoting cell proliferation and the inhibition of apoptosis.