Beta-Nicotinamide Mononucleotide Nmn CAS 1094-61-7
Detais:
Product Name: Nicotinamide
Synonyms: Pyridine-3-carboxamide; Niacinamide cell culture tested; Nicotinamide (1.06818); Niacinamide; Vitamin PP; VPP; Pyridine-3-Carboxyamide; 3-Pyridinecarboxyamide; Vitamin B3; Nicotinic acid amide; Nicotinic Amide
Assay: 99%
CAS No.: 98-92-0
EINECS No.: 202-713-4
Molecular Formula: C6H6N2O
Molecular Weight: 122.12
Density: 1.40
Melting point: 128-131º C
Boiling point: 150-160 ° C
Flashing point: 182 ° C
Water Solubillity: 1000 g/L (20 º C)
Appearance: White crystaline powder
Packing: 25kg/drum
Application: The prevention and treatment of pellagra
Description
Nicotinamide mononucleotide (“NMN” and “β-NMN”) is a nucleotide derived from ribose and nicotinamide.Niacinamide (nicotinamide) is a derivative of vitamin B3, also known as niacin. As a biochemical precursor of NAD+, it may be useful in the prevention of pellagra.Its precursor, niacin, is found in a variety of nutritional sources: peanuts, mushrooms (portobello, grilled), avocados, green peas (fresh), and certain fish and animal meats.
In studies on mice, NMN has shown to reverse age-related arterial dysfunction by decreasing oxidative stress. A long-term study indicates that NMN can slow down the physiologic decline in ageing mice. As a result, the older mice in the study have metabolism and energy levels resembling those of younger mice, with extended life spans. However, NMN did not show similar beneficial effects in young mice.
Nicotinamide Uses :
Same as nicotinic acid. Water soluble is better than niacin acid, easy to generate complex agglomerate with vitamin C. The dosage is 30-80 mg/kg.
Nicotinamide and nicotinic acid are in common use generally and nicotinic acid can transform into nicotinamide in animals. Lack of nicotinic acid and nicotinamide, results in pellagra. So they can prevent pellagra. They also play a role in the metabolism of protein and sugar, which can improve human and animal nutrition. In addition to be used as a medicine, it can also be applied in food and feed additives. The production capacity is more than 30000 tons in the world. In Japan, niacinamide used in medicine (40%), feed additives (50%) and food additives (10%). Nicotinic acid and nicotinamide are non-toxic, naturally contains in liver, kidney, yeast and honey. The niacinamide LD50 of subcutaneous injection for rat is 1.7 g/kg.
It is of Vitamin drugs, and involved in metabolic process. Can be used in skin care products, to prevent coarse skin, maintain healthy skin cells, and promote skin whitening. In addition, it can also be used in hair care products, to promote scalp blood circulation, healthy hair follicles, promotes hair growth and prevent alopecia.
Used in biochemical research. To prepare tissue culture medium. The pharmaceutical industry.
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