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High Quality Sex Enhancement Raw Powder Series Avanafil

CATEGORY AND TAGS:
Sex-enhancement items
Certification: GMP,ISO,UKAS
Model Number: 330784-47-9
Minimum Order Quantity: 10g
Delivery Time: Within 24 hours after receiving your payment
Payment Terms: West Union,Moeny Gram, Bitcoin and Bank Transfer
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  • Specifications

        High Quality Sex Enhancement Raw Powder Series Avanafil

Description:

Avanafil is a PDE5 inhibitor approved for erectile dysfunction by FDA . Avanafil acts by inhibiting a specific phosphodiesterase type 5 enzyme which is found in various body tissues, but primarily in the corpus cavernosum penis, as well as the retina. Other similar drugs are tadalafil and vardenafil. The advantage of avanafil is that it has very fast onset of action compared with other PDE5 inhibitors. It is absorbed quickly, reaching a maximum concentration in about 3045 minutes.

Usage:
It is a development of the phosphodiesterase type 5 inhibitors, for the treatment of male sexual dysfunction, at present in the America, EU and Japan have completed phase II clinical trials, phase III clinical trials will start. The product is composed of Japanese Tanabe Pharma Company and VIVUS company development. In addition to oral dosage forms, VIVUS company is also developing Avanafil urethral administration, for not responding to oral dosage forms of patients. Avanafil is a potent, highly selective phosphodiesterase 5 inhibitor, in vitro experiments showed that the selectivity of phosphodiesterase 5 stronger than sildenafil. The compound dear compliance weak against other phosphodiesterase, and effect of adenosine receptor decreased, suggesting that the cardiovascular effects of avanafil should be weaker than sildenafil. Pre clinical study showed that avanafil and organic nitrate drugs taken in combination to reduce its on blood pressure was significantly weaker than sildenafil and nitrate drugs with clothes. Moreover, avanafil inhibition of phosphodiesterase 6 is very weak, the relevant visual disturbance suppression may the enzyme phosphodiesterase 5 inhibitor induced and other.

Dosage :

For most individuals, the recommended starting dose of avanafil is 100 mg per day taken about 30 minutes before sexual activity. Depending on the adequacy of the response or side effects, the dose may be increased to 200 mg or decreased to 50 mg a day. Individuals who are taking medications that moderately increase the blood levels of avanafil should not exceed a total dose of 50 mg in 24 hours.

Lab Test Result:

 

Product name

 

Avanafil

 

CAS No.

 

330784-47-9

 

Packaging

 

1KG/Bag

 

Production date

 

2017/04/30

 

Shelf life

 

2019/04/29

 

Standard

 

IHS

 

Items

 

Specification

 

Results

 

Description

 

white or off white crystalline powder

 

white crystalline powder

 

 

Solubility

 

soluble in dimethyl sulfoxide & slightly soluble in ethanol and methanol

 

 

complies

 

 

 

Identification,HPLC

 

the principal peak in the chromatogram obtained with test solution is corresponds to retention time the principal peak in the chromatogram obtained with RS in the assay

 

 

 

complies

 

Melting point

 

132-165℃

 

163℃

 

Heavy metals

 

not more than 10ppm

 

complies

 

Loss on drying

 

not more than 0.5%

 

0.248%

 

Specific optical rotation

 

-18.0 °to -26.0°

 

-25.06°

 

Methanol

 

NMT 3000ppm

 

complies

 

Chloroform

 

NMT 60ppm

 

complies

 

Sulphated ash

 

not more than 0.1%

 

0.05%

 

Assay

 

98-102%

 

99.811%

 

Conclusion

 

Qualified

 

Sex Drug Raw Powder

 

 

Sildenafil Citrate (Viagra)

 

Vardenafil

 

Tadalafil (Cialis)

 

Vardenafil HCL

 

 

 

Yohimbine HCL

 

HCL

 

Avanafil

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