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99% Purity Chemical Powder Aicar Sarms for Bodybuilding

CATEGORY AND TAGS:
SARMs
Powder: Yes
Customized: Customized
Certification: GMP, HSE, ISO 9001, USP, BP
Suitable for: Adult
State: Solid
Purity: >99%
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  • Specifications

99% Purity Chemical Powder Aicar Sarms for Bodybuilding

Abstract

Model NO.: CZG-Sarms09
Name: Aicar
Other Name: Acadesine
CAS No.: 2627-69-2
Mf: C9h14n4o5
MW: 258.23
Einecs: 220-097-5
Usage: Fat Buring
MOQ: 1 Gram
Storage: Cool and Dry Place
Appearance: White Powder
Trademark: CZG
Transport Package: Aluminum Foil Bag or as Requirement
Specification: 10g/ bag 50g/ bag 100g/ bag etc
Origin: China Mainland
HS Code: 2937290090

Mechanism of action

The nucleoside form of AICAR, acadesine, is an analog of adenosine that enters cardiac cells to inhibit adenosine kinase and adenosine deaminase. It enhances the rate of nucleotide re-synthesis increasing adenosine generation from adenosine monophosphate only during conditions of myocardial ischemia.In cardiac myocytes, acadesine is phosphorylated to AICAR to activate AMPK without changing the levels of the nucleotides. AICAR is able to enter the de novo synthesis pathway for adenosine synthesis to inhibit adenosine deaminase causing an increase in ATP levels and adenosine levels.

 

 Application:

Aicar (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR& alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes.

Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase).

 

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